Pharmaceutical plant upgrade

The AstraZeneca facility in Sydney is a world-class pharmaceutical manufacturing plant, renowned for its advanced capabilities in producing respiratory medications. In response to growing global demand for inhaler products, the facility underwent a significant upgrade, adding three new production lines to increase output and efficiency.

Precise Air was engaged to deliver a comprehensive mechanical services solution tailored to the stringent requirements of pharmaceutical manufacturing environments.

Scope of Works

The project encompassed the full lifecycle of mechanical services delivery, including:

• Detailed Construction & Design
  Engineering and design of mechanical systems to meet cleanroom standards and pharmaceutical-grade specifications.

• Supply, Installation & Commissioning
  End-to-end delivery of mechanical infrastructure, including precision placement, rigorous testing, and seamless commissioning.

• Air Filtration & Distribution Systems
  Installation of advanced air handling systems featuring HEPA filtration to maintain sterile conditions and prevent contamination.

• HEPA Terminal Units
  Integration of high-efficiency particulate air (HEPA) terminals to ensure ultra-clean airflow within critical production zones.

• Compressed Air & Steam Scrubbers
  Deployment of specialist cleaning systems to support sterile manufacturing processes, including compressed air lines and steam scrubbers.

• Building Management System (BMS)
  Implementation of a smart BMS for real-time monitoring and control of environmental conditions, ensuring compliance with pharmaceutical standards.

• Maintenance, Defects Rectification & Warranty
  Ongoing support including scheduled maintenance, rapid defect resolution, and comprehensive warranty coverage.

Project Highlights

• Delivered in a live manufacturing environment with zero disruption to ongoing operations.

• All systems designed to meet TGA and GMP compliance standards.

• Enhanced facility capability to meet increased global demand for respiratory products.

• Collaboration with AstraZeneca’s engineering and quality teams to ensure seamless integration with existing infrastructure.